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Biology-Driven DSM Overhaul Planned by APA — 21hThe DSM, the foundational manual for psychiatry, has historically excluded biology due to preliminary science, but the APA plans to modernize the next edition with neurobiological insights. Researchers are increasingly including genetic risk, polygenic scores, and biomarkers as steps toward biology-informed, precision psychiatry, while noting that biomarkers aren’t yet ready for routine clinical use.