Otto I of Schwerin (died 1357) was a son of Count Gunzelin VI and Richardis of Tecklenburg. In 1327, he succeeded his father as Count of Schwerin.
Otto was married to Princess Mathilda of Werle, a daughter of John III of Werle. They had a daughter:
Richardis (d. 1377). She married Albert III of Mecklenburg-Schwerin (1340–1412), who was also king of Sweden.
Otto I died in 1357. He had no male heir and was succeeded by his brother Nicholas I.