Overview
Irene Palaiologina (died after 1356) was the empress consort of Matthew Kantakouzenos.
Family
Irene was a daughter of despotēs Demetrios Palaiologos and his wife, possibly Theodora Komnene. Irene's paternal grandparents were Andronikos II Palaiologos and his second wife Irene of Montferrat. The paternal uncles of Irene included Michael IX Palaiologos and Theodore I, Marquess of Montferrat. Her maternal aunt was possibly Simonida.
Empress
On 26 October 1341, her father-in-law John VI was crowned emperor at Didymoteicho. His rival John V Palaiologos reigned from Constantinople. The civil war between them lasted until 1347. On 3 February 1347, the two sides reached an agreement. John VI was accepted as senior emperor with John V as his junior co-ruler.
On 15 April 1353, Matthew was declared co-emperor and the conflict between John V and John VI restarted over what was seen as an attempt of John VI to secure his succession. Irene became thus the third Empress consort along with her mother-in-law Irene Asanina (wife of John VI) and sister-in-law Helena Kantakouzene (wife of John V).
From Wikipedia (CC BY-SA 4.0).