Prince Karl Christian Joseph of Saxony, also anglicized as Charles of Saxony, was a German prince of the House of Wettin. He was Duke of Courland and Semigallia from 1758 to 1763. Born in Dresden, he was the fifth son of Augustus III, King of Poland and Elector of Saxony, and Maria Josepha of Austria. He is an ancestor of the Italian House of Savoy.

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