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AstraZeneca — AstraZeneca plc · Public domain

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AstraZeneca

British-Swedish pharmaceutical company

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Photo: Arne Müseler / Wikimedia Commons (CC BY-SA 3.0 de)
AstraZeneca Ends Phase III Lung Cancer Trial
AstraZeneca reports a setback as its Phase III trial of volrustomig plus chemotherapy in PD-L1 negative metastatic non-small cell lung cancer is halted after an independent data review found it unlikely to meet primary endpoints, while another late-stage study in cervical cancer and other indications continues. In a positive contrast, AZN and partners SAFFRON showed that Tagrisso combined with Orpathys significantly improved progression-free and overall survival, underscoring a mixed near-term outlook but ongoing strength in its immuno-oncology pipeline.
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Facts from Wikidata (CC0). Image via Wikimedia Commons (Public domain).

Photo: FDV / Wikimedia Commons (CC BY-SA 4.0)

EU Approves Etcamah in First-Line ER+ Breast Cancer

AstraZeneca’s Etcamah (camizestrant) won EU approval to be used with CDK4/6 inhibitors as a first-line treatment for ER-positive, HER2-negative advanced breast cancer in patients with ESR1 mutations, based on SERENA-6 trial results showing a 56% reduction in progression or death. The drug already has approvals in Japan, the UAE, and Saudi Arabia, with U.S. review ongoing and the EU decision highlighting its potential to expand AstraZeneca’s oncology footprint as it targets endocrine-resistant disease.

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AstraZeneca plc (AZ) is a Swedish–British multinational pharmaceutical and biotechnology company with its headquarters at the Cambridge Biomedical Campus in Cambridge, England. It has a portfolio of products for major diseases in areas including oncology, cardiovascular, gastrointestinal, infection, neuroscience, respiratory, and inflammation.

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Country: United Kingdom, Sweden
Headquarters: Cambridge, Cambridge Biomedical Campus
Inception: 1913
Website: http://www.astrazeneca.com/

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