Antiochis was a princess of the Seleucid dynasty, daughter of Seleucus II Callinicus and Laodice II and sister of Antiochus III the Great. She may have been born in 244/243 BC as the twin sister of Seleucus III Ceraunus. In 212 BC, following his siege of Arsamosata, Antiochus III gave her in marriage to Xerxes of Sophene, making her queen consort of Sophene.