Fullmetal Alchemist

is a Japanese anime television series loosely adapted from the original manga series of the same name by Hiromu Arakawa. Comprising 51 episodes, it was produced by the animation studio Bones for Mainichi Broadcasting System and Aniplex, and directed by Seiji Mizushima. It was broadcast on MBS in Japan from October 2003 to October 2004. As in the manga, the series follows the adventures of brothers Edward and Alphonse Elric, who are searching for the Philosopher's Stone so they can regain the bodies they lost in a failed attempt to bring their dead mother back to life. During production, Arakawa requested an original ending for the anime that differed from the manga, which was still ongoing at the time. This led to the series deviating into an entirely original storyline direction halfway through its run. The first anime series concluded with a direct sequel film, Conqueror of Shamballa, released in 2005. A second anime series, Fullmetal Alchemist: Brotherhood, which faithfully adapted the entire storyline of the original manga, was broadcast in 2009. Plot The first half of the anime's plot adapts the first seven volumes of the manga. However, the plots severely diverge from each other by the middle of the story, specifically around the time where Roy Mustang's friend Maes Hughes is murdered by the homunculus Envy in disguise. Dante, a former lover of Hohenheim and mentor to the Elric brothers' teacher, is the series' central antagonist. Centuries ago, Hohenheim and Dante perfected methods for making the Philosopher's Stone and achieved immortality by transferring their souls and intellects into other bodies as they age. Hohenheim was eventually overcome with the guilt of sacrificing lives to make the Stone and left Dante. Although Dante can still jump from body to body with the last stone she and Hohenheim created, she is not willing to risk the rebound of creating one herself. She thus uses the homunculi to encourage Edward and Alphonse, along with other equally desperate Alchemists to create another complete Philosopher's Stone for her.