Crank

Crank is a 2006 American action film written and directed by Mark Neveldine and Brian Taylor in their directorial debuts. It stars Jason Statham, Amy Smart and Jose Pablo Cantillo. The title of the film comes from a slang word for methamphetamine. In the film, Chev Chelios, a Los Angeles-based hitman, is poisoned by the mafia and must keep his adrenaline flowing constantly in order to keep himself alive, while he tries to track down the man who poisoned him.