local gigantism

Local gigantism or localised gigantism is a condition in which a certain part of the body acquires larger than normal size due to excessive growth of the anatomical structures or abnormal accumulation of substances. It is more common in fingers and toes, where it is termed macrodactyly. However, sometimes an entire limb may be enlarged. Causes Local gigantism may be caused by a heterogeneous group of both congenital and acquired conditions. Congenital Congenital causes include: Klippel–Trénaunay syndrome Maffucci syndrome macrodystrophia lipomatosa neurofibromatosis, lipoatrophic diabetes. Proteus syndrome, which by one theory accounts for the deformities of the Elephant Man