Paolo Di Laura Frattura (born July 4, 1962 in Campobasso) is an Italian politician and member of the Democratic Party.
Centre-left coalition nominee for President of Molise in 2011 regional election, he lost that election against incumbent President Angelo Michele Iorio (PdL) with a small margin. In the 2013 early regional election Frattura run again against Iorio: in this election Iorio lost re-election to Frattura. Frattura has served as the President of the Italian region of Molise from 2013 to 2018, when he decided to not run for a second term in the April 2018 regional election (6 week after March 2018 Italian general election when the centre-left coalition arrived only third in the national vote and also in Molise).
His father, Fernando Di Laura Frattura, also served as the President of Molise from 1988 to 1990.