Lisa Jones

Lisa Michelle Jones (born February 1977) is an associate professor of pharmaceutical sciences at the University of Maryland, Baltimore (UMB). Her research is in structural proteomics, using mass spectrometry together with fast photochemical oxidation of proteins (FPOP), allowing researchers to study the solvent accessibility of proteins experimentally. Early life and education Jones became interested in science as a freshman at high school, where she took part in a national Science Technology Engineering Program. She earned a BS in biochemistry at Syracuse University in 1999. Jones completed her PhD at Georgia State University and specialized in structural biology. Jones received postdoctoral training in structural virology at the University of Alabama at Birmingham. She was a Pfizer postdoctoral researcher at Washington University in St. Louis working with Michael Gross on MassSpec-based protein foot-printing. Research and career After her postdoctoral research, she joined Indiana University, where she became an associate professor. She moved to the University of Maryland School of Pharmacy in 2016. In her research, Jones focusses on structural proteomics, having developed fast photochemical oxidation of proteins (FPOP) which uses an excimer laser for photolysis, which generates hydroxyl radicals. Hydroxyl radicals go on to oxidise the side chains of amino acids and provide solvent accessibility of proteins within a cell. FPOP can provide information on the sites of ligand binding, protein interaction and protein conformational changes in vivo. More recently, her group has extended the platform with a no-flow platform for high-throughput in-cell measurements.