Averages from 2021–2025 (155 days of record).
Expect May days in St Louis, Missouri to top out around 76°F and cool to about 57°F overnight, with roughly 14 days of measurable rain across the month. In recent years May has ranged from 40°F to 90°F.
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Current St Louis, Missouri forecast → · Historical data by Open-Meteo (ERA5).